Toshikatsu Okumura Selected Research

Claudin-4

11/2010	Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs.
3/2009	Troglitazone increases expression of E-cadherin and claudin 4 in human pancreatic cancer cells.

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Toshikatsu Okumura Research Topics

Disease

37	Neoplasms (Cancer) 03/2024 - 07/2002
27	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 04/2024 - 02/2015
19	Hypersensitivity (Allergy) 04/2024 - 02/2015
12	Pancreatic Neoplasms (Pancreatic Cancer) 02/2024 - 01/2004
11	Hyperalgesia 01/2020 - 12/2014
9	Stomach Neoplasms (Stomach Cancer) 03/2024 - 07/2002
6	Adenocarcinoma 03/2024 - 01/2019
5	Visceral Pain 04/2024 - 02/2016
5	Hepatocellular Carcinoma (Hepatoma) 09/2023 - 01/2004
5	Colorectal Neoplasms (Colorectal Cancer) 10/2022 - 01/2020
5	Neoplasm Metastasis (Metastasis) 09/2021 - 01/2019
5	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2020 - 01/2008
5	Fatty Liver 01/2018 - 10/2005
4	Hemorrhage 05/2024 - 01/2010
4	Crohn Disease (Crohn's Disease) 01/2024 - 12/2018
4	Non-alcoholic Fatty Liver Disease 10/2023 - 01/2018
4	Ulcerative Colitis 08/2023 - 01/2020
4	Inflammation (Inflammations) 04/2022 - 01/2021
4	Colitis 01/2021 - 08/2017
4	Nociceptive Pain 01/2018 - 02/2016
3	Carcinoma (Carcinomatosis) 03/2024 - 12/2020
3	Fever (Fevers) 12/2023 - 06/2022
3	Disease Progression 11/2023 - 03/2015
3	Fibrosis (Cirrhosis) 01/2023 - 08/2017
3	Fatigue 12/2022 - 01/2020
3	Diarrhea 06/2022 - 02/2016
3	Carcinogenesis 01/2021 - 01/2020
2	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 03/2024 - 06/2021
2	Esophageal Neoplasms (Esophageal Cancer) 03/2024 - 06/2021
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 03/2024 - 01/2021
2	Infections 07/2023 - 11/2017
2	Insulin Resistance 04/2022 - 05/2009
2	Obesity 04/2022 - 05/2009
2	Liver Diseases (Liver Disease) 03/2022 - 08/2017
2	Lymphatic Metastasis 09/2021 - 01/2019
2	Sepsis (Septicemia) 08/2021 - 12/2020
2	Ascites 08/2021 - 08/2017
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2021 - 03/2015

Drug/Important Bio-Agent (IBA)

17	LipopolysaccharidesIBA 09/2023 - 01/2017
10	Corticotropin-Releasing HormoneIBA 09/2023 - 12/2015
10	CytokinesIBA 08/2022 - 01/2017
10	PPAR gammaIBA 03/2010 - 07/2002
8	Messenger RNA (mRNA)IBA 10/2022 - 07/2002
7	OrexinsIBA 09/2023 - 11/2005
7	Proteins (Proteins, Gene)FDA Link 07/2021 - 07/2002
6	LigandsIBA 02/2010 - 07/2002
6	Troglitazone (Rezulin)FDA Link 03/2009 - 07/2002
5	Corticotropin-Releasing Hormone Receptors (Corticotropin Releasing-Hormone Receptor)IBA 08/2022 - 12/2014
5	Biomarkers (Surrogate Marker)IBA 08/2021 - 03/2010
4	FerrichromeIBA 03/2024 - 06/2017
4	Colchicine FDA LinkGeneric 12/2023 - 12/2020
4	Interleukin-1 (Interleukin 1)IBA 11/2023 - 12/2015
4	Immune Checkpoint InhibitorsIBA 07/2022 - 06/2020
4	Naloxone (Narcan)FDA LinkGeneric 07/2021 - 01/2018
4	LipidsIBA 01/2018 - 10/2005
4	ThiazolidinedionesIBA 11/2010 - 10/2009
4	Gemcitabine FDA Link 10/2009 - 03/2004
3	DNA (Deoxyribonucleic Acid)IBA 11/2023 - 01/2020
3	GhrelinIBA 11/2023 - 01/2020
3	Toll-Like Receptor 4IBA 09/2023 - 11/2018
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2023 - 05/2009
3	Prednisolone (Predate)FDA LinkGeneric 01/2023 - 01/2010
3	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 10/2022 - 01/2020
3	Small Interfering RNA (siRNA)IBA 10/2022 - 06/2020
3	astressinIBA 08/2022 - 12/2017
3	NivolumabIBA 01/2022 - 01/2019
3	MucinsIBA 01/2022 - 09/2009
3	PolyphosphatesIBA 11/2021 - 01/2020
3	IronIBA 01/2020 - 06/2017
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 11/2010 - 06/2005
3	p38 Mitogen-Activated Protein KinasesIBA 09/2005 - 03/2004
2	carbazochrome (Adona)IBA 05/2024 - 10/2022
2	Butyrates (Butyrate)IBA 04/2024 - 12/2019
2	Fluorouracil (Carac)FDA LinkGeneric 03/2024 - 01/2021
2	Long Noncoding RNAIBA 02/2024 - 01/2021
2	AcidsIBA 01/2024 - 11/2017
2	PhlorhizinIBA 11/2023 - 07/2021
2	Oxytocin (Pitocin)FDA LinkGeneric 09/2023 - 10/2022
2	NeuropeptidesIBA 09/2023 - 01/2020
2	Bevacizumab (Avastin)FDA Link 09/2023 - 12/2022
2	atezolizumabIBA 09/2023 - 12/2022
2	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2023 - 01/2018
2	beraprostIBA 01/2023 - 01/2018
2	Warfarin (Coumadin)FDA LinkGeneric 10/2022 - 01/2010
2	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 08/2022 - 11/2018
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 08/2022 - 11/2018
2	Toll-Like Receptors (Toll-Like Receptor)IBA 04/2022 - 07/2021
2	AntibodiesIBA 07/2021 - 01/2021
2	Evans Blue (Blue, Evans)FDA Link 07/2021 - 11/2020
2	RNA-Binding Proteins (RNA-Binding Protein)IBA 06/2021 - 01/2020
2	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 01/2020
2	Dextran SulfateIBA 01/2021 - 01/2021
2	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2020

Therapy/Procedure

21	Therapeutics 01/2024 - 03/2004
6	Drug Therapy (Chemotherapy) 01/2022 - 06/2018
3	Remission Induction 01/2024 - 08/2021
3	Blood Component Removal (Apheresis) 01/2024 - 08/2021
3	Chemoradiotherapy 01/2021 - 08/2016
3	Gastrectomy 01/2021 - 09/2019
2	Immunotherapy 09/2023 - 07/2021